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Cocaine chiefly affects the perceptiveness's reward arrangement about blocking the reuptake of neurotransmitters, only dopamine. This leads to an accumulation of dopamine in the synapses, creating feelings of pleasure and reinforcing the behavior of cocaine use. On the other hand, prolonged employ of cocaine alters the brain's chemistry, leading to dependence and addiction to cocaine.
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The avail oneself of of cocaine carries significant health risks. Short-term effects of cocaine incorporate increased centre rate, illustrious blood pressure, and heightened essence temperature, which can bring on to serious cardiovascular issues, including focus attacks and strokes related to cocaine use. Long-term use of cocaine can outcome in primitive psychological and physical strength problems, such as angst, paranoia, and respiratory issues. Additionally, the embryonic as far as something cocaine overdose is a judgemental concern, as flush with small amounts can lead to devastating outcomes.

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